Page Content
Cell Handling by Dielectrophoresis
- © IHP/Gringel
Subjecting a biological cell in solution to an inhomogeneous electrical field may elicit a dipole moment that can interact with the field.
Photonic Biosensors
- © IHP/Birkholz
Within the framework of a DFG-funded project, an optical biosensor chip is being developed at the Joint Lab, in which the detection is performed by a microring resonators.
Monitoring of Bioprocesses
- © IHP/Birkholz
The monitoring of small biomolecules represents an important task in the control of bioprocesses. Despite this importance, even after decades of research and development, problems of reproducibility, sensor drift and receptor stability are still being struggled with.
Additive Manufacturing for Lab-on-Chip
- © IHP/Birkholz
3D printing or additive manufacturing processes in general have made electrical integration processes much easier. In various projects such as the MRR-DEP biosensor or DEP-based cell separation, the required experimental systems are manufactured using AM processes.
High-frequency Impedance Spectroscopy for Cell Monitoring
- © IHP/Jamal
Impedance measurements of cell suspensions represent a well-established technique for determining the density of cells and their electrical properties. It only deserves a parallel plate capacitor or a comparable arrangement between which the cell ensemble has to be suspended.
Biocompatibility
- Korrodierter Bio-Halbleiterkontakt
- © IHP/Birkholz
The surfaces of processed semiconductors become unstable when exposed to bio milieus. In particular, aqueous solutions of electrolytes may easily cause corrosion of inorganic surfaces like Si, SiO2, SiON. Also biological materials degrade upon contact, for which the denaturation of proteins on Si/SiO2 surfaces is a well-known example.